$ATNM “Lion Stock Alerts” Promoter Rank: 19/21 Actinium Pharmaceuticals, Inc. Newsletter 7:36:35 AM March 24, 2021

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ATNM Promotional Newsletter

The following is a newsletter released by "Lion Stock Alerts" promoting Actinium Pharmaceuticals, Inc.


The following newsletter has not been verified for accuracy or completeness.


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New Alert Actinium Pharmaceuticals, Inc. NYSE ATNM

ATNM is a clinical-stage biopharmaceutical company developing ARCs or Antibody Radiation-Conjugates, which combine the targeting ability of antibodies with the cell killing ability of radiation.

The company is focused on three primary areas

Bone Marrow Transplant BMT
Multiple Myeloma
Acute Myeloid Leukemia AML

A bone marrow transplant is a procedure that infuses healthy blood-forming stem cells into your body to replace your damaged or diseased bone marrow.

Doctors use these transplants to treat people with certain diseases, such as Multiple Myeloma and Leukemia.

Sadly, multiple myeloma is the second most common blood cancer diagnosis.

The companys lead application for ARCs is targeted conditioning, which is intended to selectively deplete a patient's disease or cancer cells and certain immune cells.

In addition, the company is developing a multi-disease, multi-target pipeline of clinical-stage ARCs.

Plus, underpinning the companys clinical programs is their proprietary AWE Antibody Warhead Enabling technology platform.

As the company recently explained

The intellectual property encompassing Actinium's AWE technology platform covers its gold standard linker technology, methods of ARC manufacture in addition to methods of use for ARCs in multiple diseases, including indication, dose and scheduling, radionuclide warhead, and therapeutic combinations.

Actinium's AWE technology patent portfolio includes 30 patent families comprised of over 135 issued or pending global patent applications, of which 10 are issued and 24 pending in the United States.

Over the past few months, the company has announced multiple developments that could position it for further growth.

In December, the company announced

Actinium Announces Successful Pre-Planned Ad Hoc Interim Analysis of Phase 3 SIERRA trial

Here are the highlights from this press release

100% rate of BMT and engraftment in patients receiving therapeutic dose of Iomab-B and lower rates of sepsis and sepsis related Grade 3 adverse events compared to patients receiving salvage therapies at 75% enrollment recently highlighted in oral presentations at ASH 2020 Annual Meeting
Independent Data Monitoring Committee recommends SIERRA continue as planned to full enrollment of 150 patients trial is currently over 75% enrolled
SIERRA trial remains the only randomized Phase 3 trial to offer potentially curative bone marrow transplant as an option for patients with active relapsed or refractory AML

In January, the company announced

Actinium and Astellas Announce Research Collaboration Focused on Novel Actinium-225 Based Targeted Radiotherapies

Here are some of the companys comments from this press release

Sandesh Seth, Chairman and Chief Executive Officer of Actinium, added, Through our development efforts, Actinium has established itself as a leader in the field of Actinium-225 based targeted radiotherapies. We have amassed the most experience treating patients with Actinium-225 via our CD33 program's several Actimab-A trials and have gained important insights in developing targeted radiotherapies through the execution of the Actimab-A and also SIERRA Phase 3 pivotal trial for our lead asset, Iomab-B. This expertise and experience with radiopharmaceuticals has been invaluable to us and we believe will also be to Astellas in this collaboration. As Iomab-B and Actimab-A advance in the clinic with multiple clinical milestones upcoming from each of our trials, we look forward to executing this collaboration and furthering the field of targeted radiotherapy with Astellas.

Over the past few months, the company has participated in multiple conferences

Actinium Highlights Presence at Targeted Radiopharmaceuticals Summit

Actinium to Participate in a Fireside Chat at the B. Riley Oncology Investor Conference
Actinium Announces Participation in BIO CEO Investor Digital Conference
Actinium Showcases Targeted Conditioning Program with 2 Oral Presentations Highlighting Iomab-B and Pivotal Phase 3 SIERRA Trial at 2021 Transplantation Cellular Therapy Annual Meeting
Actinium Announces Participation in H.C. Wainwright Global Life Sciences Conference

In March, the company announced

Actinium Announces Appointment of Mark Kubik, MBA as Chief Business Officer

Here are the highlights from this press release

Mr. Kubik joins Actinium with over 25 years of experience in transformative and award-winning BD and MA transactions
Proven deal making abilities in the empowered antibody, biologics and gene therapy fields strongly suited to Actinium's AWE technology platform and Antibody Radiation Conjugates for targeted conditioning

In addition, recently the company announced

Actinium to Highlight Expansion of Targeted Conditioning Portfolio at AACR with Next-Generation Actinium-225-Based CD45 Targeting ARC

Here are the highlights from this press release

Positive preclinical data support continued development with strong potential in bone marrow transplant, adoptive cell therapy and gene therapy applications
Potent alpha emitter Actinium-225 targeted to CD45 cells demonstrates positive biodistribution profile and dose-dependent conditioning capabilities

Plus, just this morning, the company announced

Actinium Announces Initiation of Patient Enrollment in Iomab-ACT Trial for Targeted Conditioning Prior to CD19 CAR T-Cell Therapy

ATNM could present increased growth potential.

Make sure to do your own due diligence.

Sources , , , , , , , , , , , , , ,

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