$ATNM “Lion Stock Alerts” Promoter Rank: 19/21 Actinium Pharmaceuticals, Inc. Newsletter 7:34:21 AM March 25, 2021

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ATNM Promotional Newsletter

The following is a newsletter released by "Lion Stock Alerts" promoting Actinium Pharmaceuticals, Inc.

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The following newsletter has not been verified for accuracy or completeness.

LionStockAlerts

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Hello

ATNM, our newest alert, released breaking news this morning that could be another growth catalyst for the company.

Actinium Announces Completion of Enrollment of Second Dose Cohort in Actimab-A Venetoclax Combination Trial for Patients with RR AML

Here are the highlights from this press release

Proof-of-concept Phase 1 data expected in 2H2021 will evaluate safety, response rates, MRD negativity and cytogenetic profiles
Complete response in patient with TP53 and other mutations and one partial response reported in patient with poor risk adverse cytogenetics reported in first dose cohort with subtherapeutic dose of Actimab-A with venetoclax

As the company further explained

Dr. Mark Berger, Actinium's Chief Medical Officer, said, We are encouraged by the strong progress we are making in this novel combination trial and excited to be studying Actimab-A with venetoclax. Venetoclax has emerged as a standard of care and backbone therapy for patients with AML who are both fit and unfit, however, patients with relapsed or refractory disease have poor outcomes and therefore need better treatment options. Based on the synergistic mechanism of action and preliminary clinical evidence from the first cohort, we are optimistic that Actimab-A in combination with venetoclax can improve outcomes for patients with relapsed or refractory disease using the unique targeted radiation mechanism of Actimab-A. We look forward to presenting data from this cohort of patients as well additional clinical data from the Phase 1 portion of the trial and working to advance this novel combination in the clinic.

Here are the companys comments from this press release

Sandesh Seth, Actinium's Chairman and CEO, added, This trial is an exciting evolution of our Actimab-A program and application of the isotope Actinium-225. Actinium-225 is a potent medical isotope that can kill a cancer cell with a single alpha particle hit, emits four alpha particles in its decay and can cause double strand DNA breaks for which cancer cells have no known repair or resistance mechanism. Its energy is also emitted over a very short path length equal to a few cells in diameter enabling precise cell killing while sparing normal cells to limit systemic toxicities. With clinical experience in nearly 150 patients, robust IP and a clinically validated supply chain, we are leaders in the rapidly growing field of targeted alpha radiotherapy and specifically Actinium-225. Through continued clinical progress and innovation driven by our RD efforts, we are committed to advancing our leadership position in the field of Actinium-225 based therapies and applying them with the goal of improving patient outcomes.

ATNM opened Wednesday at 8.58 and rallied to a high of 8.92, before closing the day at 8.30.

As the company further accomplishes its plans, it could position itself for increased opportunity.

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